Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2016 Oct 1;47(10):960-964.
doi: 10.3928/23258160-20161004-11.

Analysis of Scleral Feeder Vessel in Myopic Choroidal Neovascularization Using Optical Coherence Tomography Angiography

Ricardo Noguera Louzada, Daniela Ferrara, Eduardo Amorim Novais, Eric Moult, Emily Cole, Mark Lane, James Fujimoto, Jay S Duker, Caroline R Baumal
Case Reports

Analysis of Scleral Feeder Vessel in Myopic Choroidal Neovascularization Using Optical Coherence Tomography Angiography

Ricardo Noguera Louzada et al. Ophthalmic Surg Lasers Imaging Retina. .

Abstract

To describe the appearance of a scleral-derived feeder vessel in a highly myopic eye with secondary choroidal neovascularization (CNV) as visualized on both en face high-speed swept-source (SS) optical coherence tomography angiography (OCTA) prototype, and a commercially available spectral-domain (SD) OCTA, with the corresponding en face and cross-sectional structural OCT images. In this case report, a 60-year-old white male presented with high myopia and secondary CNV in the right eye, previously treated with anti-vascular endothelial growth factor, and was imaged on both SD-OCT and SS-OCT. The neovascular complex could be visualized on both devices. Structural en face SS-OCT images demonstrated a large choroidal-scleral feeder vessel that was not visualized with SD-OCT. The authors concluded that structural en face SS-OCT better visualizes scleral feeder vessel compared to SD-OCT due to the longer wavelength (∼1,050 nm) with increased choroidal penetration and decreased sensitivity roll-off in the SS-OCT system. [Ophthalmic Surg Lasers Imaging Retina. 2016;47:960-964.].

PubMed Disclaimer

Figures

Figure 1
Figure 1
High myopia and secondary choroidal neovascularization (CNV) active in the right eye. Optical coherence tomography angiography (OCTA) 6 mm × 6 mm on spectral-domain (SD)-OCTA device showing the CNV (A) (white head arrow) surrounded with projection artifacts or decorrelation tails. On structural en face OCT (B), white head arrow indicates the CNV and the feeder vessel projection. The OCT B-scan high-definition one-line scan using SD-OCT shows the CNV (C) (white arrow) with pigment epithelium detachment and subretinal fluid.
Figure 2
Figure 2
Spectral-domain optical coherence tomography angiography (SD-OCTA) from the right eye demonstrates multiples depths of scans (A, B, C, D). OCTA (upper row), en face structural OCT (middle row), and cross-sectional OCT (lower row) are shown. (A, B, C, D) White head arrows indicate the choroidal neovascularization and white arrows indicate the feeder vessel in all scans.
Figure 3
Figure 3
(A) 3-D Orthoplane view using 3-D Slicer (a free open-source software application for medical image computing available at http://www.slicer.org) from the right eye with X-fast and Y-fast swept-source optical coherence tomography (SS-OCT) cross-sectional scans, on top of structural en face OCT centered on the choroidal neovascularization (CNV). (B, C, D) Orthogonal view with the (C) en face structural scan and the corresponding (D) X-fast OCT cross-sectional scan and the (B) Y-fast cross-sectional scan. White arrow (A, B, C, D) indicates the feeder vessel.
See this image and copyright information in PMC

References

    1. Kotsolis AI, Killian FA, Ladas ID, Yannuzzi LA. Fluorescein angiography and optical coherence tomography concordance for choroidal neovascularisation in multifocal choroidtis. Br J Ophthalmol. 2010;94(11):1506–1508. - PubMed
    1. Makita S, Hong Y, Yamanari M, Yatagai T, Yasuno Y. Optical coherence angiography. Opt Express. 2006;14(17):7821–7840. - PubMed
    1. Fingler J, Schwartz D, Yang C, Fraser SE. Mobility and transverse flow visualization using phase variance contrast with spectral domain optical coherence tomography. Opt Express. 2007;15(20):12636–12653. - PubMed
    1. Tao YK, Davis AM, Izatt JA. Single-pass volumetric bidirectional blood flow imaging spectral domain optical coherence tomography using a modified Hilbert transform. Opt Express. 2008;16(16):12350–12361. - PubMed
    1. An L, Wang RK. In vivo volumetric imaging of vascular perfusion within human retina and choroids with optical microangiography. Opt Express. 2008;16(15):11438–11452. - PubMed