When to start a renal replacement therapy in acute kidney injury (AKI) patients: many irons in the fire

Stefano Romagnoli¹, Zaccaria Ricci²

Affiliations

¹ Department of Anesthesia and Critical Care, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy;; Department of Health Science, University of Florence, Florence, Italy.
² Depatment of Cardiology and Cardiac Surgery, Pediatric Cardiac Intensive Care Unit, Bambino Gesù Children's Hospital, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy.

PMID: 27761459
PMCID: PMC5066036
DOI: 10.21037/atm.2016.08.55

Editorial

When to start a renal replacement therapy in acute kidney injury (AKI) patients: many irons in the fire

Stefano Romagnoli et al. Ann Transl Med. 2016 Sep.

. 2016 Sep;4(18):355.

doi: 10.21037/atm.2016.08.55.

Authors

Stefano Romagnoli¹, Zaccaria Ricci²

Affiliations

¹ Department of Anesthesia and Critical Care, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy;; Department of Health Science, University of Florence, Florence, Italy.
² Depatment of Cardiology and Cardiac Surgery, Pediatric Cardiac Intensive Care Unit, Bambino Gesù Children's Hospital, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy.

PMID: 27761459
PMCID: PMC5066036
DOI: 10.21037/atm.2016.08.55

No abstract available

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Conflict of interest statement

The authors have no conflicts of interest to declare.

Comment in

Timing of renal replacement therapy in critically ill patients with acute kidney injury.
Meersch M, Schmidt C, Schmidt J, Zarbock A. Meersch M, et al. Ann Transl Med. 2016 Sep;4(18):360. doi: 10.21037/atm.2016.09.05. Ann Transl Med. 2016. PMID: 27775733 Free PMC article. No abstract available.

Comment on

Initiation Strategies for Renal-Replacement Therapy in the Intensive Care Unit.
Gaudry S, Hajage D, Schortgen F, Martin-Lefevre L, Pons B, Boulet E, Boyer A, Chevrel G, Lerolle N, Carpentier D, de Prost N, Lautrette A, Bretagnol A, Mayaux J, Nseir S, Megarbane B, Thirion M, Forel JM, Maizel J, Yonis H, Markowicz P, Thiery G, Tubach F, Ricard JD, Dreyfuss D; AKIKI Study Group. Gaudry S, et al. N Engl J Med. 2016 Jul 14;375(2):122-33. doi: 10.1056/NEJMoa1603017. Epub 2016 May 15. N Engl J Med. 2016. PMID: 27181456 Clinical Trial.
Effect of Early vs Delayed Initiation of Renal Replacement Therapy on Mortality in Critically Ill Patients With Acute Kidney Injury: The ELAIN Randomized Clinical Trial.
Zarbock A, Kellum JA, Schmidt C, Van Aken H, Wempe C, Pavenstädt H, Boanta A, Gerß J, Meersch M. Zarbock A, et al. JAMA. 2016 May 24-31;315(20):2190-9. doi: 10.1001/jama.2016.5828. JAMA. 2016. PMID: 27209269 Clinical Trial.

Cited by

Preemptive kidney support: an optimal practice or a good theory?
Ricci Z, Ferrari F, Romagnoli S. Ricci Z, et al. Ann Transl Med. 2020 Apr;8(7):422. doi: 10.21037/atm.2020.03.96. Ann Transl Med. 2020. PMID: 32395466 Free PMC article. No abstract available.
[Renal replacement therapy in acute kidney injury].
Klein SJ, Joannidis M. Klein SJ, et al. Med Klin Intensivmed Notfmed. 2017 Jun;112(5):437-443. doi: 10.1007/s00063-017-0290-0. Epub 2017 May 2. Med Klin Intensivmed Notfmed. 2017. PMID: 28466293 Review. German.
Optimal timing of initiating CRRT in patients with acute kidney injury after liver transplantation.
Ren A, Li Z, Zhang X, Deng R, Ma Y. Ren A, et al. Ann Transl Med. 2020 Nov;8(21):1361. doi: 10.21037/atm-20-2352. Ann Transl Med. 2020. PMID: 33313106 Free PMC article.
Early versus delayed initiation of renal replacement therapy for acute kidney injury: an updated systematic review, meta-analysis, meta-regression and trial sequential analysis of randomized controlled trials.
Moreira FT, Palomba H, Chaves RCF, Bouman C, Schultz MJ, Serpa Neto A. Moreira FT, et al. Rev Bras Ter Intensiva. 2018 Jul-Sept;30(3):376-384. doi: 10.5935/0103-507X.20180054. Rev Bras Ter Intensiva. 2018. PMID: 30328991 Free PMC article.
Debate: Intermittent Hemodialysis versus Continuous Kidney Replacement Therapy in the Critically Ill Patient: Moderator Commentary.
Palevsky PM. Palevsky PM. Clin J Am Soc Nephrol. 2023 May 1;18(5):644-646. doi: 10.2215/CJN.0000000000000116. Epub 2023 Feb 9. Clin J Am Soc Nephrol. 2023. PMID: 36758153 Free PMC article.

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References

1. KDIGO AKI Work Group KDIGO clinical practice guideline for acute kidney injury. Kidney Int Suppl. 2012;2:1-138.
1. Kellum JA, Mehta RL, Levin A, et al. Development of a clinical research agenda for acute kidney injury using an international, interdisciplinary, three-step modified Delphi process. Clin J Am Soc Nephrol 2008;3:887-94. 10.2215/CJN.04891107 - DOI - PubMed
1. Palevsky PM, Baldwin I, Davenport A, et al. Renal replacement therapy and the kidney: minimizing the impact of renal replacement therapy on recovery of acute renal failure. Curr Opin Crit Care 2005;11:548-54. 10.1097/01.ccx.0000179936.21895.a3 - DOI - PubMed
1. Zarbock A, Kellum JA, Schmidt C, et al. Effect of Early vs Delayed Initiation of Renal Replacement Therapy on Mortality in Critically Ill Patients With Acute Kidney Injury: The ELAIN Randomized Clinical Trial. JAMA 2016;315:2190-9. 10.1001/jama.2016.5828 - DOI - PubMed
1. Gaudry S, Hajage D, Schortgen F, et al. Initiation Strategies for Renal-Replacement Therapy in the Intensive Care Unit. N Engl J Med 2016;375:122-33. 10.1056/NEJMoa1603017 - DOI - PubMed

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When to start a renal replacement therapy in acute kidney injury (AKI) patients: many irons in the fire

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When to start a renal replacement therapy in acute kidney injury (AKI) patients: many irons in the fire

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