Comparative Study
Microscarring in skeletal muscle after repeated exposures to lidocaine with epinephrine
- PMID: 277638
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Comparative Study
Microscarring in skeletal muscle after repeated exposures to lidocaine with epinephrine
J Oral Surg.
1978 Jul.
Abstract
To assess the effect of repeated exposures to clinically used local anesthetic, rat thighs were given up to five supramuscular injections of 2% lidocaine with epinephrine, 1:50,000. Substantial damage to muscles followed by rapid regeneration occurred; however, in some areas evidence of retarded regeneration of muscles and microscarring was observed.
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