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. 2017 Jan:464:200-201.
doi: 10.1016/j.cca.2016.10.023. Epub 2016 Oct 17.

Evaluation of the LDBIO point of care test for the combined detection of toxoplasmic IgG and IgM

Emmanuelle Chapey  1 , Martine Wallon  2 , François Peyron  3
Affiliations

Evaluation of the LDBIO point of care test for the combined detection of toxoplasmic IgG and IgM

Emmanuelle Chapey et al. Clin Chim Acta. 2017 Jan.

Abstract

The toxoplasma ICT IgG-IgM rapid diagnostic test for the simultaneous detection of specific toxoplasmic immunoglobulin (Ig) G and IgM was compared with the Architect fully automated chemiluminescence test. Four hundred sera were included, among which 248 scored negative in Architect. The cassettes were easily read with the naked eye. Diagnostic sensitivity and specificity were 97% and 96%, respectively. The test scored 8 false-positive IgG and yielded negative results in 3 sera displaying unspecific IgM in Architect. The LDBIO appears to be a reliable first line test, although the false-positive results for IgG deserve further investigation. Such an easily performed test could be used advantageously for screening for toxoplasmosis in pregnant women.

Keywords: Diagnostic; POC; Toxoplasma ICT IgG-IgM; Toxoplasmosis.

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