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. 1989 Aug 1;7(2):137-9.
doi: 10.1016/0168-8227(89)90104-6.

Fructose-related glycation

M Oimomi  1 , T Nakamichi, T Ohara, M Sakai, N Igaki, F Hata, S Baba
Affiliations

Fructose-related glycation

M Oimomi et al. Diabetes Res Clin Pract. .

Abstract

We investigated in vitro the effect of the polyol pathway on the formation of advanced Maillard reaction products which have fluorescence and cross-links. Bovine serum albumin supplemented with various concentrations of glucose, fructose or sorbitol was incubated for 14 days. The fluorescence intensity was higher after incubation with fructose than after incubation with glucose. However, no significant increase in fluorescence intensity was found after incubation with sorbitol. These results suggest that in the polyol pathway fructose plays an important role in the formation of advanced Maillard products.

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