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. 2016 Oct 21;15(1):115.
doi: 10.1186/s12938-016-0236-4.

3D-printing techniques in a medical setting: a systematic literature review

Philip Tack  1 , Jan Victor  2 , Paul Gemmel  3 , Lieven Annemans  4
Affiliations

3D-printing techniques in a medical setting: a systematic literature review

Philip Tack et al. Biomed Eng Online. .

Abstract

Background: Three-dimensional (3D) printing has numerous applications and has gained much interest in the medical world. The constantly improving quality of 3D-printing applications has contributed to their increased use on patients. This paper summarizes the literature on surgical 3D-printing applications used on patients, with a focus on reported clinical and economic outcomes.

Methods: Three major literature databases were screened for case series (more than three cases described in the same study) and trials of surgical applications of 3D printing in humans.

Results: 227 surgical papers were analyzed and summarized using an evidence table. The papers described the use of 3D printing for surgical guides, anatomical models, and custom implants. 3D printing is used in multiple surgical domains, such as orthopedics, maxillofacial surgery, cranial surgery, and spinal surgery. In general, the advantages of 3D-printed parts are said to include reduced surgical time, improved medical outcome, and decreased radiation exposure. The costs of printing and additional scans generally increase the overall cost of the procedure.

Conclusion: 3D printing is well integrated in surgical practice and research. Applications vary from anatomical models mainly intended for surgical planning to surgical guides and implants. Our research suggests that there are several advantages to 3D-printed applications, but that further research is needed to determine whether the increased intervention costs can be balanced with the observable advantages of this new technology. There is a need for a formal cost-effectiveness analysis.

Keywords: 3D printing; Additive manufacturing; Anatomic model; Customized; Innovation; Patient specific; Review; Surgery.

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Figures

Fig. 1
Fig. 1
Search strategy and reasons for exclusion
Fig. 2
Fig. 2
Overview of selected papers based on publication year
Fig. 3
Fig. 3
Overview of the usage of 3D-printing techniques as percentage of total number of papers
Fig. 4
Fig. 4
Overview of papers per specific field
See this image and copyright information in PMC

References

    1. Wurm G, Tomancok B, Pogady P, Holl K, Trenkler J. Cerebrovascular stereolithographic biomodeling for aneurysm surgery. J Neurosurg. 2004;100(1):139–145. doi: 10.3171/jns.2004.100.1.0139. - DOI - PubMed
    1. D’Urso PS, Thompson RG, Atkinson RL, Weidmann MJ, Redmond MJ, Hall BI, et al. Cerebrovascular biomodelling: a technical note. Surg Neurol. 1999;52(5):490–500. doi: 10.1016/S0090-3019(99)00143-3. - DOI - PubMed
    1. Izatt MT, Thorpe PLPJ, Thompson RG, D’Urso PS, Adam CJ, Earwaker JWS, et al. The use of physical biomodelling in complex spinal surgery. Eur Spine J. 2007;16(9):1507–1518. doi: 10.1007/s00586-006-0289-3. - DOI - PMC - PubMed
    1. D’Urso PS, Earwaker WJ, Barker TM, Redmond MJ, Thompson RG, Effeney DJ, et al. Custom cranioplasty using stereolithography and acrylic. Br J Plast Surg. 2000;53(3):200–204. doi: 10.1054/bjps.1999.3268. - DOI - PubMed
    1. Brie J, Chartier T, Chaput C, Delage C, Pradeau B, Caire F, et al. A new custom made bioceramic implant for the repair of large and complex craniofacial bone defects. J Cranio-Maxillofac Surg. 2013;41(5):403–407. doi: 10.1016/j.jcms.2012.11.005. - DOI - PubMed

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