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. 2016 Sep 19;8(3):6626.
doi: 10.4081/pr.2016.6626.

Sternal Osteomyelitis after Bacillus Calmette-Guérin Vaccination

Affiliations

Sternal Osteomyelitis after Bacillus Calmette-Guérin Vaccination

Rolandas Selvestravičius et al. Pediatr Rep. .

Abstract

Presented here is the case of a nine-month-old boy with the osteomyelitis of the upper area sternum caused by bacillus Calmette-Guerin (BCG), the Danish 1331 strain vaccine against tuberculosis. Upon examination, a swelling of approximately 2×3 cm diameter was observed in the upper sternal area. The mass was hard, fixed and sensitive to palpation with no local skin hyperaemia. Chest X-rays revealed a round mass anterior to the sternum, suggesting a diagnosis of osteomyelitis. A consequent sternal biopsy was performed and Mycobacterium bovis BCG was identified by a positive growth culture.

Keywords: Adverse reactions; BCG osteomyelitis; BCG vaccine; Tuberculosis.

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Conflict of interest statement

the authors declare no potential conflict of interest.

Figures

Figure 1.
Figure 1.
Computed tomography without contrast-enhanced axial and multi planar reconstruction sagittal images show the mass in the anterior mediastinum, around the manubrium of sternum.
Figure 2.
Figure 2.
Axial contrast-enhanced computed tomography showing that the mass is reducing around sternum.

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