Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016:2016:7893413.
doi: 10.1155/2016/7893413. Epub 2016 Sep 29.

Abdominal Aortic Aneurysm Repair: Results from a Series of Young Patients

Pasqualino Sirignano  1 , Francesco Speziale  1 , Nunzio Montelione  1 , Chiara Pranteda  1 , Giuseppe Galzerano  2 , Wassim Mansour  1 , Enrico Sbarigia  1 , Carlo Setacci  2
Affiliations

Abdominal Aortic Aneurysm Repair: Results from a Series of Young Patients

Pasqualino Sirignano et al. Biomed Res Int. 2016.

Abstract

Objectives. To compare durability and survival after endovascular aneurysm repair (EVAR) and open repair (OR) of abdominal aortic aneurysms (AAAs) in young patients. Material and Methods. A retrospective study was conducted between 2005 and 2014 on all consecutive patients of 60 years of age or younger. Measures considered for analysis were reintervention related to AAA, laparotomy and access vessel injury during EVAR, and all-cause mortality during hospitalization and follow-up. Results. Seventy out of 119 patients were treated by OR (58.8%) and 49 (41.2%) by EVAR, 9 in off-label fashion (18.3%). Technical success was achieved in all cases. No AAA-related death was recorded. Overall in-hospital mortality was zero and the reintervention rate was 2.5% (3/119: 1/70 OR, 2/49 EVAR, p = 0.36). There is no death at 30-day or 1-year follow-up. Thirty-day reintervention rate was 1.6% (2/119; 0/70 OR, 2/49 EVAR, p = 0.16), while the 1-year rate was 2.5% (3/119; 1/70 OR, 2/49 EVAR, p = 0.36). At the mean follow-up of 56.8 ± 42.7 months, mortality and reintervention rates were 5.8% (7/119; 3/70 OR, 4/49 EVAR, p = 0.38) and 10% (12/119; 8/70 OR, 4/49 EVAR, p = 0.39), respectively. The overall reintervention rate, mortality, and freedom from adverse events did not differ between the two groups. No differences in outcome were recorded between patients treated by EVAR in on-label versus off-label fashion. Conclusion. Our (albeit limited) experience suggests that, in an unselected young patient population undergoing elective AAA repair, OR or EVAR can be performed safely with similar immediate and long term outcomes.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Kaplan-Meier estimates of freedom from reintervention; standard error never exceeded 10%.
Figure 2
Figure 2
Kaplan-Meier estimates of freedom from any adverse event; standard error never exceeded 10%.
See this image and copyright information in PMC

References

    1. Parodi J. C., Palmaz J. C., Barone H. D. Transfemoral intraluminal graft implantation for abdominal aortic aneurysms. Annals of Vascular Surgery. 1991;5(6):491–499. doi: 10.1007/BF02015271. - DOI - PubMed
    1. Diehm N., Tsoukas A. I., Katzen B. T., et al. Matched-pair analysis of endovascular versus open surgical repair of abdominal aortic aneurysms in young patients at low risk. Journal of Vascular and Interventional Radiology. 2008;19(5):645–651. doi: 10.1016/j.jvir.2007.12.445. - DOI - PubMed
    1. Sachs T., Schermerhorn M., Pomposelli F., Cotterill P., O'Malley J., Landon B. Resident and fellow experiences after the introduction of endovascular aneurysm repair for abdominal aortic aneurysm. Journal of Vascular Surgery. 2011;54(3):881–888. doi: 10.1016/j.jvs.2011.03.008. - DOI - PMC - PubMed
    1. Karthikesalingam A., Holt P. J., Vidal-Diez A., et al. Predicting aortic complications after endovascular aneurysm repair. British Journal of Surgery. 2013;100(10):1302–1311. doi: 10.1002/bjs.9177. - DOI - PubMed
    1. Torsello G., Troisi N., Donas K. P., Austermann M. Evaluation of the Endurant stent graft under instructions for use vs off-label conditions for endovascular aortic aneurysm repair. Journal of Vascular Surgery. 2011;54(2):300–306. doi: 10.1016/j.jvs.2010.12.062. - DOI - PubMed

LinkOut - more resources