Radical Enantioselective C(sp3 )-H Functionalization
- PMID: 27781361
- DOI: 10.1002/anie.201609105
Radical Enantioselective C(sp3 )-H Functionalization
Abstract
Radical style: Several breakthroughs have recently been achieved in enantioselective C(sp3 )-H functionalization through radical activation. These new strategies show how radical chemistry can be used to convert alkanes into functionalized chiral molecules (see scheme; HAT=hydrogen atom transfer).
Keywords: C−H functionalization; asymmetric synthesis; copper catalysis; photoredox catalysis; radical activation.
© 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
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