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. 2016 Oct;161(6):792-796.
doi: 10.1007/s10517-016-3512-1. Epub 2016 Oct 26.

Pulsed Dendritic Cells for the Therapy of Experimental Glioma

I V Chekhonin  1 , O I Gurina  2 , S A Cherepanov  3 , M A Abakumov  3 , K P Ionova  2 , D K Zhigarev  2 , A V Makarov  2 , V P Chekhonin  2   3
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Pulsed Dendritic Cells for the Therapy of Experimental Glioma

I V Chekhonin et al. Bull Exp Biol Med. 2016 Oct.

Erratum in

Abstract

We obtained the morphologically, cytofluorometrically, and functionally mature dendritic cells from rats that were pulsed with antigens of the C6 glioma tissue extract. The concentrations of angiogenesis antigens (VEGF, VEGFR-1, and VEGFR-2) and periglioma zone proteins (GFAP, connexin 43, and BSAT1) in the pulsing extract were measured by ELISA. Our results drove us to a conclusion that despite mature phenotype of pulsed dendritic cell, the antigenic composition of glioma tissue extracts should be modified.

Keywords: angiogenesis; dendritic cells; glioma; neurospecific proteins; periglioma zone.

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