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Case Reports
. 2012 Oct;5(5):211-214.
doi: 10.4021/gr469w. Epub 2012 Sep 20.

Corticosteroids in the Treatment of Pseudomembranous Colitis: A Report of 3 Cases

Ella Sykes  1 , Patrick McDonald  2 , Paul K Flanagan  3
Affiliations
Case Reports

Corticosteroids in the Treatment of Pseudomembranous Colitis: A Report of 3 Cases

Ella Sykes et al. Gastroenterology Res. 2012 Oct.

Abstract

Clostridium difficile associated diarrhoea has been an increasing problem in the last decade in the UK and is a cause of significant morbidity. At the most severe end of the spectrum it causes pseudomembranous colitis which has a significant associated mortality rate and can be refractory to standard treatments. Here we present three cases of proven pseudomembranous colitis in which systemic corticosteroids were used as an adjunct to treatment, raising the possibility of a new treatment option for this difficult condition.

Keywords: Clostridium; Colitis; Corticosteroids; Pseudomembranous.

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Figures

Figure 1
Figure 1
Endoscopy showing a classic pseudomembranous appearance, with multiple plaques from the rectum to the distal sigmoid.
See this image and copyright information in PMC

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