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. 2017 Jun;58(6):1512-1514.
doi: 10.1080/10428194.2016.1248964. Epub 2016 Oct 27.

Haplo-cord transplant: HLA-matching determines graft dominance

Koen van Besien  1 , Nebu Koshy  1 , Usama Gergis  1 , Sebastian Mayer  1 , Melissa Cushing  1 , Hannah Rennert  1 , Ronit Reich-Slotky  1 , Tomer Mark  1 , Roger Pearse  1 , Adriana Rossi  1 , Adrienne Phillips  1 , Liljana Vasovic  1 , Rosanna Ferrante  1 , Yen-Michael Hsu  1 , Tsiporah Shore  1
Affiliations

Haplo-cord transplant: HLA-matching determines graft dominance

Koen van Besien et al. Leuk Lymphoma. 2017 Jun.
No abstract available

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Conflict of interest statement

Conflict of Interest:

Coauthors report no conflict.

Figures

Figure 1
Figure 1
Relation between HLA-match of Haplo-graft and percentage day 56 UCB Chimerism in CD33 lineage
See this image and copyright information in PMC

References

    1. Lindemans CA, van Besien K. Topping it up: methods to improve cord blood transplantation outcomes by increasing the number of CD34+ cells. Cytotherapy. 2015;17(6):723–729. - PubMed
    1. Liu H, van Besien K. Alternative donor transplantation--"mixing and matching": the role of combined cord blood and haplo-identical donor transplantation (haplo-cord SCT) as a treatment strategy for patients lacking standard donors? Curr Hematol Malig Rep. 2015;10(1):1–7. - PubMed
    1. Kwon M, Bautista G, Balsalobre P, et al. Haplo-cord transplantation using CD34+ cells from a third-party donor to speed engraftment in high-risk patients with hematologic disorders. Biol Blood Marrow Transplant. 2014;20(12):2015–2022. - PubMed
    1. Liu H, Rich ES, Godley L, et al. Reduced-intensity conditioning with combined haploidentical and cord blood transplantation results in rapid engraftment, low GVHD, and durable remissions. Blood. 2011;118(24):6438–6445. - PMC - PubMed
    1. van Besien K, Hari P, Zhang MJ, et al. Reduced intensity haplo plus single cord transplant compared to double cord transplant: improved engraftment and survival free of progression and GVHD (GRFS) Haematologica. 2016 - PMC - PubMed

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