Performing a Better Bone Marrow Aspiration
- PMID: 27788908
- DOI: 10.1016/j.pmr.2016.06.009
Performing a Better Bone Marrow Aspiration
Abstract
Bone marrow aspiration (BMA) is increasingly being used to harvest stem cells for use in regenerative medicine. The focus of BMA in interventional orthopedics is to maximize the yield of mesenchymal stem cells. The authors present an improved method for BMA that involves fluoroscope or ultrasound guidance combined with anesthesia; in the authors' experience, it produces the highest possible stem cell yield and is well tolerated by patients. The authors provide a step-by-step guide to the process, along with a discussion of technical and other considerations and quick reference guides for ultrasound- and fluoroscope-guided BMA.
Keywords: Bone marrow aspiration; Bone marrow aspiration technique; Bone marrow stem cells; Image-guided bone marrow aspiration; Stem cells.
Copyright © 2016 Elsevier Inc. All rights reserved.
Similar articles
-
Bone marrow aspiration for regenerative orthopedic intervention: technique with ultrasound guidance for needle placement.Regen Med. 2017 Dec;12(8):917-928. doi: 10.2217/rme-2017-0109. Epub 2017 Sep 11. Regen Med. 2017. PMID: 28891421
-
A qualitative and quantitative analysis of autologous human multipotent adult stem cells derived from three anatomic areas by marrow aspiration: tibia, anterior ilium, and posterior ilium.Int J Oral Maxillofac Implants. 2013 Sep-Oct;28(5):e290-4. doi: 10.11607/jomi.te10. Int J Oral Maxillofac Implants. 2013. PMID: 24066346
-
Only prolonged time from abstraction found to affect viable nucleated cell concentrations in vertebral body bone marrow aspirate.Spine J. 2014 Jun 1;14(6):990-5. doi: 10.1016/j.spinee.2013.10.021. Epub 2013 Nov 1. Spine J. 2014. PMID: 24184640
-
Bone Marrow-Derived Cellular Therapies in Orthopaedics: Part I: Recommendations for Bone Marrow Aspiration Technique and Safety.JBJS Rev. 2018 Nov;6(11):e4. doi: 10.2106/JBJS.RVW.18.00007. JBJS Rev. 2018. PMID: 30461435 Review. No abstract available.
-
Bone marrow stromal cells (bone marrow-derived multipotent mesenchymal stromal cells) for bone tissue engineering: basic science to clinical translation.Int J Biochem Cell Biol. 2011 Mar;43(3):286-9. doi: 10.1016/j.biocel.2010.12.006. Epub 2010 Dec 13. Int J Biochem Cell Biol. 2011. PMID: 21147252 Review.
Cited by
-
Ultrasound imaging and guidance in the management of knee osteoarthritis in regenerative medicine field.J Clin Orthop Trauma. 2019 Jan-Feb;10(1):24-31. doi: 10.1016/j.jcot.2018.11.015. Epub 2018 Nov 30. J Clin Orthop Trauma. 2019. PMID: 30705527 Free PMC article. Review.
-
Bone marrow aspirate clot: A feasible orthobiologic.J Clin Orthop Trauma. 2020 Oct;11(Suppl 5):S789-S794. doi: 10.1016/j.jcot.2020.07.003. Epub 2020 Jul 19. J Clin Orthop Trauma. 2020. PMID: 32999557 Free PMC article. Review.
-
Bone Marrow Aspirate Concentrate Is Equivalent to PRP for the Treatment of Knee OA at 1 Year: Letter to the Editor.Orthop J Sports Med. 2020 Oct 30;8(10):2325967120960706. doi: 10.1177/2325967120960706. eCollection 2020 Oct. Orthop J Sports Med. 2020. PMID: 33195724 Free PMC article. No abstract available.
-
Simulation-based Bone Marrow Aspiration and Trephine Biopsy Education for Medical Students: A Non-randomized Controlled Trial.Intern Med. 2025 Feb 15;64(4):527-533. doi: 10.2169/internalmedicine.3998-24. Epub 2024 Jul 18. Intern Med. 2025. PMID: 39019605 Free PMC article.
-
Percutaneous autologous bone marrow concentrate for knee osteoarthritis: patient-reported outcomes and progenitor cell content.Int Orthop. 2022 Oct;46(10):2219-2228. doi: 10.1007/s00264-022-05524-9. Epub 2022 Aug 6. Int Orthop. 2022. PMID: 35932306 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical