Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2017 Apr;15(2):183-187.
doi: 10.1016/j.clgc.2016.09.004. Epub 2016 Sep 19.

Current Role of Radiotherapy for Renal-Cell Carcinoma: Review

Natalia Dengina  1 , Ilya Tsimafeyeu  2 , Timur Mitin  3
Affiliations
Review

Current Role of Radiotherapy for Renal-Cell Carcinoma: Review

Natalia Dengina et al. Clin Genitourin Cancer. 2017 Apr.

Abstract

Surgery is the standard of care for patients with renal-cell carcinoma (RCC). Radiotherapy (RT) can decrease the risk of local recurrence after surgery and can lead to excellent outcomes in patients unfit for surgery. We reviewed clinical experience with various forms of RT, including conventional fractionated RT and intraoperative radiotherapy (IORT) as adjunct to surgery, hypofractionated high-dose stereotactic body radiotherapy (SBRT), and particle therapy in unresectable RCC. We discuss future directions for using RT in the treatment of RCC. We encourage clinicians to incorporate RT modalities in prospective clinical trials.

Keywords: Intraoperative radiotherapy; Particle therapy; Radioresistance; Radiosensitivity; Stereotactic body radiotherapy; Targeted therapy.

PubMed Disclaimer