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Review
. 2016 Oct 14:9:325-335.
doi: 10.2147/CEG.S96676. eCollection 2016.

Managing inflammatory bowel disease in pregnancy: current perspectives

Matthew Pinder  1 , Katie Lummis  1 , Christian P Selinger  2
Affiliations
Review

Managing inflammatory bowel disease in pregnancy: current perspectives

Matthew Pinder et al. Clin Exp Gastroenterol. .

Abstract

Inflammatory bowel disease (IBD) affects many women of childbearing age. The course of IBD is closely related to pregnancy outcomes with poorly controlled IBD increasing the risk of prematurity, low weight for gestation, and fetal loss. As such, women with IBD face complex decision making weighing the risks of active disease versus those of medical treatments. This review summarizes the current evidence regarding the safety and efficacy of IBD treatments during pregnancy and lactation aiming to provide up-to-date guidance for clinicians. Over 50% of women have poor IBD- and pregnancy-related knowledge, which is associated with views contrary to medical evidence and voluntary childlessness. This review highlights the effects of poor patient knowledge and critically evaluates interventions for improving patient knowledge and outcomes.

Keywords: Crohn’s disease; breast feeding; inflammatory bowel disease; nursing; pregnancy; ulcerative colitis.

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Conflict of interest statement

CPS has received unrestricted research grants from Warner Chilcott and AbbVie; has provided consultancy to Warner Chilcott, Dr Falk, AbbVie, and Takeda; and had speaker arrangements with Warner Chilcott, Dr Falk, AbbVie, MSD, and Takeda. The other authors report no conflict of interest in this work.

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References

    1. van der Woude CJ, Ardizzone S, Bengtson MB, et al. The second European evidenced-based consensus on reproduction and pregnancy in inflammatory bowel disease. J Crohns Colitis. 2015;9(2):107–124. - PubMed
    1. Mountifield RE, Prosser R, Bampton P, Muller K, Andrews JM. Pregnancy and IBD treatment: this challenging interplay from a patients’ perspective. J Crohns Colitis. 2010;4(2):176–182. - PubMed
    1. Mountifield R, Bampton P, Prosser R, Muller K, Andrews JM. Fear and fertility in inflammatory bowel disease: a mismatch of perception and reality affects family planning decisions. Inflamm Bowel Dis. 2009;15(5):720–725. - PubMed
    1. Dubinsky M, Abraham B, Mahadevan U. Management of the pregnant IBD patient. Inflamm Bowel Dis. 2008;14(12):1736–1750. - PubMed
    1. Marri SR, Ahn C, Buchman AL. Voluntary childlessness is increased in women with inflammatory bowel disease. Inflamm Bowel Dis. 2007;13(5):591–599. - PubMed