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Case Reports
. 2016 Sep;10(9):OD05-OD06.
doi: 10.7860/JCDR/2016/22215.8483. Epub 2016 Sep 1.

Unexplained Persistent Hyperglycaemia in a Type I Diabetes Patient - Is Injection Site Lipohypertrophy the Cause?

Ranjana Ajit Sahasrabudhe  1 , Tejas Yashwant Limaye  2 , Vidya Sanjay Gokhale  3
Affiliations
Case Reports

Unexplained Persistent Hyperglycaemia in a Type I Diabetes Patient - Is Injection Site Lipohypertrophy the Cause?

Ranjana Ajit Sahasrabudhe et al. J Clin Diagn Res. 2016 Sep.

Abstract

Type I diabetes patients depend on insulin injections. Proper injection technique is essential for good glycaemic control. Incorrect technique can also lead to local injection site adverse effects, commonest being lipohypertrophy. Hypoglycaemia, by far the most dreaded adverse effect of insulin, receives utmost focus in management of patients on insulin. Lipohypertrophy, on the other hand, is a relatively neglected adverse effect. It is necessary for health care providers to realize that it can also have serious clinical implications. We present a case of persistent unexplained hyperglycaemia in a Type I Diabetes Mellitus (TIDM) patient with severe injection site lipohypertropy. After switching to normal unused sites, her blood sugar levels improved, along with reduction in insulin requirement. The case highlights the importance of continuous patient education and alert monitoring by health care providers.

Keywords: Insulin injection technique; Patient education; Site rotation.

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Figures

[Table/Fig-1a,b]:
[Table/Fig-1a,b]:
Injection sites showing lipohypertrophy on antero-medial aspect of thighs a: Massive lipohypertrophy at visit 1 b: Reduced lipohypertrophy six months after discontinuing the use of this site.
See this image and copyright information in PMC

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