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. 2017 Feb;162(2):535-542.
doi: 10.1007/s00705-016-3127-x. Epub 2016 Oct 28.

Epidemiology and etiology of hand, foot, and mouth disease in Fujian province, 2008-2014

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Epidemiology and etiology of hand, foot, and mouth disease in Fujian province, 2008-2014

Yuwei Weng et al. Arch Virol. 2017 Feb.

Abstract

Millions of cases of hand, foot, and mouth disease (HFMD) have been reported annually in mainland China since 2008. In this study, we investigated the epidemiology and etiology of an HFMD epidemic in Fujian province, which is located in subtropical southeastern China. Our study found similar epidemiological features of HFMD in southern areas of China, including seasonality and demographic distribution, as well as correlation between severity of illness and serotype. At least 22 serotypes of other enterovirus co-circulating with enterovirus 71 were found to belong to clade C4a, and those circulating with coxsackievirus A16 were associated with clades B1a and B1b.

Keywords: Enterovirus; Epidemiology; Etiology; Hand, foot, and mouth disease.

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