Putting T cells to work-outsourcing neoantigen detection in head and neck cancers?

R Xiao^{1

2

3}, C Van Waes¹, N C Schmitt^{1

4}

Affiliations

¹ Tumor Biology Section, Head and Neck Surgery Branch, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD, USA.
² NIH Medical Research Scholars Program, National Institutes of Health, Bethesda, MD, USA.
³ Cleveland Clinic Lerner College of Medicine, Cleveland, OH, USA.
⁴ Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins School of Medicine, Baltimore, MD, USA.

PMID: 27797438
PMCID: PMC5411338
DOI: 10.1111/odi.12604

Comment

Putting T cells to work-outsourcing neoantigen detection in head and neck cancers?

R Xiao et al. Oral Dis. 2017 Oct.

. 2017 Oct;23(7):820-821.

doi: 10.1111/odi.12604. Epub 2016 Nov 28.

Authors

R Xiao^{1

2

3}, C Van Waes¹, N C Schmitt^{1

4}

Affiliations

¹ Tumor Biology Section, Head and Neck Surgery Branch, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD, USA.
² NIH Medical Research Scholars Program, National Institutes of Health, Bethesda, MD, USA.
³ Cleveland Clinic Lerner College of Medicine, Cleveland, OH, USA.
⁴ Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins School of Medicine, Baltimore, MD, USA.

PMID: 27797438
PMCID: PMC5411338
DOI: 10.1111/odi.12604

No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: none to declare

Comment on

Targeting of cancer neoantigens with donor-derived T cell receptor repertoires.
Strønen E, Toebes M, Kelderman S, van Buuren MM, Yang W, van Rooij N, Donia M, Böschen ML, Lund-Johansen F, Olweus J, Schumacher TN. Strønen E, et al. Science. 2016 Jun 10;352(6291):1337-41. doi: 10.1126/science.aaf2288. Epub 2016 May 19. Science. 2016. PMID: 27198675

References

1. Allen CT, Clavijo PE, Van Waes C, Chen Z. Anti-Tumor Immunity in Head and Neck Cancer: Understanding the Evidence, How Tumors Escape and Immunotherapeutic Approaches. Cancers (Basel) 2015;7:2397–414. - PMC - PubMed
1. Cancer Genome Atlas Network. Comprehensive genomic characterization of head and neck squamous cell carcinomas. Nature. 2015;517:576–82. - PMC - PubMed
1. Carreno BM, Magrini V, Becker-Hapak M, et al. Cancer immunotherapy. A dendritic cell vaccine increases the breadth and diversity of melanoma neoantigen-specific T cells. Science. 2015;348:803–8. - PMC - PubMed
1. Chow LQM, Haddad R, Gupta S, et al. Antitumor Activity of Pembrolizumab in Biomarker-Unselected Patients With Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma: Results From the Phase Ib KEYNOTE-012 Expansion Cohort. J Clin Oncol 2016 - PMC - PubMed
1. Ferris RL. Immunology and Immunotherapy of Head and Neck Cancer. J Clin Oncol. 2015;33:3293–304. - PMC - PubMed

Publication types

Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions

Substances

Actions

Grants and funding

ZIA DC000090/ImNIH/Intramural NIH HHS/United States

LinkOut - more resources

Full Text Sources
Other Literature Sources
- scite Smart Citations

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Putting T cells to work-outsourcing neoantigen detection in head and neck cancers?

Affiliations

Putting T cells to work-outsourcing neoantigen detection in head and neck cancers?

Authors

Affiliations

Conflict of interest statement

Comment on

References

Publication types

MeSH terms

Substances

Grants and funding

LinkOut - more resources

Full Text Sources

Other Literature Sources