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Comment
. 2016 Nov 1;194(9):1047-1049.
doi: 10.1164/rccm.201605-0920ED.

Catching a Disease: A Molecular Trap as a Therapy for Pulmonary Arterial Hypertension

Beth L Roman  1 , Cynthia St Hilaire  1
Affiliations
Comment

Catching a Disease: A Molecular Trap as a Therapy for Pulmonary Arterial Hypertension

Beth L Roman et al. Am J Respir Crit Care Med. .
No abstract available

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Figures

Figure 1.
Figure 1.
Imbalanced transforming growth factor-β (TGF-β) superfamily signaling in pulmonary arterial hypertension (PAH). Increased TGF-β receptor signaling and decreased bone morphogenetic protein (BMP) receptor signaling contribute to PAH disease pathology. A combined strategy using ligand traps to decrease TGF-β1/3 receptor signaling, and drugs to potentiate BMP signaling, may be most effective in ameliorating PAH.
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