Randomized controlled clinical trial of 2 types of hydroxyapatite-coated implants on moderate periodontitis patients

Abstract

Purpose: The aim of this study was to compare and analyze the peri-implant tissue conditions and prospective clinical outcomes associated with 2 types of hydroxyapatite (HA)-coated implants: (1) fully HA-coated implants and (2) partially HA-coated implants with resorbable blast medium on the coronal portion of the threads.

Methods: Forty-four partially edentulous patients were randomly assigned to undergo the placement of 62 HA-coated implants, and were classified as the control group (partially HA-coated, n=30) and the test group (fully HA-coated, n=32). All patients had chronic periodontitis with moderate crestal bone loss around the edentulous area. The stability and clinical outcomes of the implants were evaluated using the primary and secondary implant stability quotient (ISQ), as well as radiographic, mobility, and peri-implant soft tissue assessments around the implants. The Wilcoxon signed-rank test and the Mann-Whitney test were used to evaluate differences between and within the 2 groups, with P values <0.05 considered to indicate statistical significance.

Results: The fully HA-coated implants displayed good retention of crestal bone, and insignificant differences were found in annual marginal bone loss between the 2 types of HA-coated implants (P>0.05). No significant differences were found in the survival rate (group I, 100%; group II, 100%) or the success rate (group I, 93.3%; group II, 93.8%). The fully HA-coated implants also did not significantly increase the risk of peri-implantitis (P>0.05).

Conclusions: The fully HA-coated implants did not lead to an increased risk of peri-implantitis and showed good retention of the crestal bone, as well as good survival and success rates. Our study suggests that fully HA-coated implants could become a reliable treatment alternative for edentulous posterior sites and are capable of providing good retention of the crestal bone.

Keywords: Dental implants; Durapatite; Osseointegration; Periodontitis; Surface properties.

Figure 1

Comparison of the 2 types of implant coatings. (A) Partially hydroxyapatite (HA)-coated implant fixture with resorbable blast medium on the coronal portion of the threads (2 mm). (B) Fully HA-coated implant fixture.

Figure 2

Standardized periapical radiographs. (A) Radiograph taken at the time of provisional crown connection. (B) Radiograph taken 1 year after loading.

Figure 3

Consolidated Standards of Reporting Trials flow diagram of the participants and the implants that were placed. HA, hydroxyapatite; RFA, resonance frequency analysis; ISQ, implant stability quotient.