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. 2016 Apr;46(2):58-61.
doi: 10.4274/tjo.29567. Epub 2016 Apr 5.

Retinal Nerve Fiber Layer Thicknesses in Three Different Optic Nerve Head Size Groups Measured by Cirrus Spectral Domain Optical Coherence Tomography

Sirel Gür Güngör  1 , Ahmet Akman  1 , Ali Küçüködük  1 , Meriç Çolak  2
Affiliations

Retinal Nerve Fiber Layer Thicknesses in Three Different Optic Nerve Head Size Groups Measured by Cirrus Spectral Domain Optical Coherence Tomography

Sirel Gür Güngör et al. Turk J Ophthalmol. 2016 Apr.

Abstract

Objectives: To compare the retinal nerve fiber layer (RNFL) thicknesses in three different optic nerve head (ONH) size groups measured by Cirrus spectral domain optical coherence tomography (OCT).

Materials and methods: Between January and March 2013, 253 eyes of 253 healthy subjects were enrolled in this study (mean age: 42.7±7.4 years [28-62 years]; 121 men and 132 women). The patients were divided into 3 groups according to ONH size: 77 patients in the "small ONH" group (ONH area <1.63 mm2), 90 patients in the "medium ONH" group (ONH area 1.63-1.97 mm2), and 86 patients in the "large ONH" group (ONH area >1.97 mm2).

Results: There were significant differences in superior (p=0.008), inferior (p=0.004) and average RNFL thickness (p=0.001) between the small, medium and large ONH groups. Positive correlations between ONH size and inferior/average RNFL thicknesses were significant but very weak (r=0.150, p=0.017 and r=0.157, p=0.013 respectively).

Conclusion: RNFL thickness as measured by Cirrus OCT is positively correlated with ONH size and the differences in RNFL thickness were statistically significant between groups. This correlation and difference may be the result of a varying distance between the circular scan and the ONH margin.

Keywords: Retinal nerve fiber layer; optic nerve head; optical coherence tomography.

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Conflict of interest statement

No conflict of interest was declared by the authors. Financial Disclosure: The authors declared that this study received no financial support.

Figures

Figure 1
Figure 1. Scatter plot showing the correlation between average retinal nerve fiber layer thickness and optic nerve head area. RNFL: Retinal nerve fiber layer
Figure 2
Figure 2. Scatter plot showing the correlation between inferior retinal nerve fiber layer thickness and optic nerve head area. RNFL: Retinal nerve fiber layer
See this image and copyright information in PMC

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