Pediatric Exposures to Ionizing Radiation: Carcinogenic Considerations
- PMID: 27801855
- PMCID: PMC5129267
- DOI: 10.3390/ijerph13111057
Pediatric Exposures to Ionizing Radiation: Carcinogenic Considerations
Abstract
Children are at a greater risk than adults of developing cancer after being exposed to ionizing radiation. Because of their developing bodies and long life expectancy post-exposure, children require specific attention in the aftermath of nuclear accidents and when radiation is used for diagnosis or treatment purposes. In this review, we discuss the carcinogenic potential of pediatric exposures to ionizing radiation from accidental, diagnostic, and therapeutic modalities. Particular emphasis is given to leukemia and thyroid cancers as consequences of accidental exposures. We further discuss the evidence of cancers that arise as a result of radiotherapy and conclude the review with a summary on the available literature on the links between computer tomography (CT) and carcinogenesis. Appropriate actions taken to mitigate or minimize the negative health effects of pediatric exposures to ionizing radiation and future considerations are discussed.
Keywords: cancer; children’s health; computed tomography; radiation.
Conflict of interest statement
The authors declare no conflict of interest.
References
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- Brenner A.V., Tronko M.D., Hatch M., Bogdanova T.I., Oliynik V.A., Lubin J.H., Zablotska L.B., Tereschenko V.P., McConnell R.J., Zamotaeva G.A., et al. I-131 dose response for incident thyroid cancers in Ukraine related to the Chornobyl accident. Environ. Health Perspect. 2011;119:933–939. doi: 10.1289/ehp.1002674. - DOI - PMC - PubMed
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- United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) Sources, Effects and Risks of Ionizing Radiation: United Nations Scientific Committee on the Effects of Atomic Radiation: UNSCEAR 2013 Report to the General Assembly with Scientific Annexes. UNSCEAR; Vienna, Austria: 2013.
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