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Case Reports
. 2016 Nov;111(11):1664-1666.
doi: 10.1038/ajg.2016.419.

Volumetric Mapping of Barrett's Esophagus and Dysplasia With en face Optical Coherence Tomography Tethered Capsule

Kaicheng Liang  1 , Osman O Ahsen  1 , Hsiang-Chieh Lee  1 , Zhao Wang  1 , Benjamin M Potsaid  1   2 , Marisa Figueiredo  3 , Vijaysekhar Jayaraman  4 , Alex E Cable  2 , Qin Huang  3   5 , Hiroshi Mashimo  3   5 , James G Fujimoto  1
Affiliations
Case Reports

Volumetric Mapping of Barrett's Esophagus and Dysplasia With en face Optical Coherence Tomography Tethered Capsule

Kaicheng Liang et al. Am J Gastroenterol. 2016 Nov.
No abstract available

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Conflict of interest statement

Guarantor of the article : James G. Fujimoto, PhD. Potential competing interests: The other authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
(a) En face OCT obtained by averaging from ~200 to 280 µm below esophageal surface. Only the distal 12 cm out of 24 cm data is shown. Dark regions are due to noncontact of the capsule with the esophagus. Scale bar 1 cm. (b) Representative cross-section (blue) from EMR region (red). Scale bar 1 mm. (c) Photograph of capsule. Scale bar 1 cm. (d) Enlargement (pink) from (b) showing layer effacement, surface signal greater than subsurface, and multiple dilated glands (arrows). (e) Cross-section (brown) showing layered BE, which is likely non-dysplastic. (f) Cross-section (yellow) showing the squamo-columnar junction at a tongue of BE. Inset scale bars 1 mm.
Figure 2
Figure 2
(a) En face OCT (red) enlarged from Figure 1a (averaged from ~200 to 280 µm depth) showing the region from which EMR was taken, with irregular mucosal patterns (circled). (b) Deeper en face OCT from same region as (a) (averaged from ~400–480 µm depth) showing dilated glands (arrows). (c) En face OCT (green) from Figure 1a (~200 to 280 µm depth) showing regular circular and ridged/villous mucosal patterns (circled), likely non-dysplastic BE. Inset scale bars 1 mm. (d) EMR histopathology showing LGD. (e) Endoscopic NBI image of EMR region.
See this image and copyright information in PMC

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