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. 2016 Dec;122(5):235.
doi: 10.1080/13813455.2016.1238940. Epub 2016 Nov 3.

Mass spectrometry in life science research

Stefan Lehr  1 , Daniel Markgraf  2
Affiliations

Mass spectrometry in life science research

Stefan Lehr et al. Arch Physiol Biochem. 2016 Dec.

Abstract

Investigating complex signatures of biomolecules by mass spectrometry approaches has become indispensable in molecular life science research. Nowadays, various mass spectrometry-based omics technologies are available to monitor qualitative and quantitative changes within hundreds or thousands of biological active components, including proteins/peptides, lipids and metabolites. These comprehensive investigations have the potential to decipher the pathophysiology of disease development at a molecular level and to monitor the individual response of pharmacological treatment or lifestyle intervention.

Keywords: 2DE; Mass spectrometry; proteomics.

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