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Comment
. 2016 Nov 3;128(18):2194-2195.
doi: 10.1182/blood-2016-09-736983.

Gene therapy simplified

Jiaqiang Ren  1 , David F Stroncek  1
Affiliations
Comment

Gene therapy simplified

Jiaqiang Ren et al. Blood. .

Abstract

In this issue of Blood, Richter et al report their work on an in vivo gene transduction system using the adenovirus-based vector and hyperactive SB transposase (SB100×) system. Their results show that this system is effective and safe and performs without needing ex vivo expansion and transduction of hematopoietic stem cells (HSCs). This system may overcome some of the difficulties associated with cell collection and manufacturing and provide technical advances for the field of gene therapy.

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Conflict of interest statement

Conflict-of-interest disclosure: The authors declare no competing financial interests.

Comment on

References

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