Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2016 Nov 3;19(5):567-568.
doi: 10.1016/j.stem.2016.10.010.

The Epigenome and Cancer Stem Cell Fate: Connected by a Linker Histone Variant

Guillermo A Orsi  1 , Monica Naughtin  1 , Geneviève Almouzni  2
Affiliations
Free article
Comment

The Epigenome and Cancer Stem Cell Fate: Connected by a Linker Histone Variant

Guillermo A Orsi et al. Cell Stem Cell. .
Free article

Abstract

The molecular features underlying tumor heterogeneity and the role of chromatin components in regulating cell fate within tumors are not well understood. Recently in Science, Torres et al. (2016) showed that the linker histone variant H1.0 functions as a chromatin switch that determines self-renewal versus differentiation decisions in cancer stem cells.

PubMed Disclaimer

Comment on

LinkOut - more resources