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Comment
. 2016 Nov 3;167(4):894-896.
doi: 10.1016/j.cell.2016.10.040.

The Human Functional Genomics Project: Understanding Generation of Diversity

Jenna L Pappalardo  1 , David A Hafler  2
Affiliations
Free article
Comment

The Human Functional Genomics Project: Understanding Generation of Diversity

Jenna L Pappalardo et al. Cell. .
Free article

Abstract

Generation of biologic diversity is a cornerstone of immunity, yet the tools to investigate the causal influence of genetic and environmental factors have been greatly limited. Studies from the Human Functional Genomics Project, presented in Cell and other Cell Press journals, integrate environmental and genetic factors with the direction and magnitude of immune responses to decipher inflammatory disease pathogenesis.

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  • A Functional Genomics Approach to Understand Variation in Cytokine Production in Humans.
    Li Y, Oosting M, Smeekens SP, Jaeger M, Aguirre-Gamboa R, Le KTT, Deelen P, Ricaño-Ponce I, Schoffelen T, Jansen AFM, Swertz MA, Withoff S, van de Vosse E, van Deuren M, van de Veerdonk F, Zhernakova A, van der Meer JWM, Xavier RJ, Franke L, Joosten LAB, Wijmenga C, Kumar V, Netea MG. Li Y, et al. Cell. 2016 Nov 3;167(4):1099-1110.e14. doi: 10.1016/j.cell.2016.10.017. Cell. 2016. PMID: 27814507
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