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. 2017 Jan;27(1):323-329.
doi: 10.1007/s10895-016-1961-6. Epub 2016 Nov 4.

A Fluorescein-Based Colorimetric and Fluorescent Probe for Hydrazine and its Bioimaging in Live Cells

Gongchun Li  1 , Yongxiang Liu  2 , Jianhua Song  2 , Yong Ye  3
Affiliations

A Fluorescein-Based Colorimetric and Fluorescent Probe for Hydrazine and its Bioimaging in Live Cells

Gongchun Li et al. J Fluoresc. 2017 Jan.

Abstract

A turn-on fluorescent probe (FN) for detection of hydrazine has been developed. Probe FN exhibited high selectivity and excellent sensitivity towards hydrazine with a detection limit as low as 4.6 × 10-10 M. Probe FN selectively reacts with hydrazine (N2H4) in a physiological environment, leading to an off-on fluorescence response along with the color change from colorless to yellow, allowing colorimetric detection of hydrazine by the naked eye. Furthermore, probe FN was successfully applied for visualizing hydrazine in living cells.

Keywords: Fluorescein; Fluorescence; Hydrazine.

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References

    1. Chem Rev. 2012 Mar 14;112(3):1910-56 - PubMed
    1. Org Lett. 2013 Nov 1;15(21):5412-5 - PubMed
    1. Org Lett. 2011 Oct 7;13(19):5260-3 - PubMed
    1. Chem Commun (Camb). 2008 Jan 14;(2):166-8 - PubMed
    1. J Hazard Mater. 2007 Jun 1;144(1-2):348-54 - PubMed

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