Predisposing factors for pancreatic adenocarcinoma: What is the role of imaging?

Abstract

Early detection of pancreatic adenocarcinoma is the goal of imaging, enabling curative surgery. The identification of high-grade dysplastic precursor lesions is even more beneficial. Two forms are now better known: pancreatic intraepithelial neoplasia (PanIN) and intraductal papillary mucinous neoplasm (IPMN). To detect these lesions with imaging, we need to know the patterns associated with them. A screening program could then be used to pinpoint them. This program could not be applied to the entire population. Identifying patients with an increased risk of pancreas adenocarcinoma is the first step of such screening.

Keywords: CT; IPMN; MRI; PanIN; Pancreas adenocarcinoma.