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Review
. 2017 Mar:56:263-267.
doi: 10.1016/j.ijid.2016.10.018. Epub 2016 Nov 2.

Novel approaches to tuberculosis vaccine development

Stefan H E Kaufmann  1 , January Weiner  2 , C Fordham von Reyn  3
Affiliations
Free article
Review

Novel approaches to tuberculosis vaccine development

Stefan H E Kaufmann et al. Int J Infect Dis. 2017 Mar.
Free article

Abstract

Tuberculosis (TB) remains the deadliest infectious disease. The widely used bacille Calmette-Guérin (BCG) vaccine offers only limited protection against TB. New vaccine candidates for TB include subunit vaccines and inactivated whole-cell vaccines, as well as live mycobacterial vaccines. Current developments in TB vaccines are summarized in this review.

Keywords: Post-exposure vaccine; Pre-exposure vaccine; Preventive vaccine; Subunit vaccine; Therapeutic vaccine; Whole-cell vaccine.

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