Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2017 May;50(3):250-253.
doi: 10.5946/ce.2016.109. Epub 2016 Nov 7.

Evaluation and Endoscopic Management of Esophageal Submucosal Tumor

Affiliations
Review

Evaluation and Endoscopic Management of Esophageal Submucosal Tumor

Weon Jin Ko et al. Clin Endosc. 2017 May.

Abstract

Submucosal tumors (SMTs) originate from tissues that constitute the submucosal layer and muscularis propria, and are covered by normal mucosa. Esophageal SMTs are rare, accounting for <1% of all esophageal tumors. However, the recent widespread use of endoscopy has led to a rapid increase in incidental detection of SMTs in Korea. Esophageal SMTs are benign in ≥90% of cases, but the possibility of malignancies such as gastrointestinal stromal tumor and malignant leiomyosarcoma still exists. Therefore, patients undergo resection in the presence of symptoms or the possibility of a malignant tumor. For resection of esophageal SMTs, surgical resection was the only option available in case of possible malignancy, but minimally invasive surgery by endoscopic resection is becoming more preferable to surgical resection with the development of endoscopic ultrasonography, endoscopic techniques, and other devices.

Keywords: Endoscopic resection; Endosonography; Submucosal tumor.

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: The authors have no financial conflicts of interest.

Figures

Fig. 1.
Fig. 1.
Tru-Cut biopsy using a flexible endoscope for the diagnosis of submucosal tumor (SMT). (A) SMT observed by using a flexible endoscope. (B) On endoscopic ultrasonography, the SMT is located in the muscularis propria. (C) Tru-Cut biopsy using a flexible endoscope. (D) Specimens.
Fig. 2.
Fig. 2.
Application of the three-dimensional printing technique for the side-hole cap during endoscpic mucosal resection with a cap-fitted endoscope applied to a submucosal tumor (SMT). (A) An esophageal SMT. (B) Submucosal injection. (C) Snaring for SMT. (D) Resection of the lesion.

References

    1. Emory TS, Sobin LH, Lukes L, Lee DH, O’Leary TJ. Prognosis of gastrointestinal smooth-muscle (stromal) tumors: dependence on anatomic site. Am J Surg Pathol. 1999;23:82–87. - PubMed
    1. Mutrie CJ, Donahue DM, Wain JC, et al. Esophageal leiomyoma: a 40-year experience. Ann Thorac Surg. 2005;79:1122–1125. - PubMed
    1. Kim MC. Endoscopic incidence of upper gastrointestinal submucosal tumors and endosonographic findings [dissertation] Suwon: Ajou University School of Medicine; 2008.
    1. Ha TI, Kim GH, Eum JS, et al. Catheter probe endoscopic ultrasonography using the jelly-filled method for esophageal subepithelial lesions. Korean J Gastrointest Endosc. 2008;36:125–131.
    1. Gress F, Schmitt C, Savides T, et al. Interobserver agreement for EUS in the evaluation and diagnosis of submucosal masses. Gastrointest Endosc. 2001;53:71–76. - PubMed

LinkOut - more resources