Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2016 Oct 25:8:645-648.
doi: 10.2147/CLEP.S99471. eCollection 2016.

Danish Pancreatic Cancer Database

Claus Fristrup  1 , Sönke Detlefsen  2 , Carsten Palnæs Hansen  3 , Morten Ladekarl  4
Affiliations
Review

Danish Pancreatic Cancer Database

Claus Fristrup et al. Clin Epidemiol. .

Abstract

Aim of database: The Danish Pancreatic Cancer Database aims to prospectively register the epidemiology, diagnostic workup, diagnosis, treatment, and outcome of patients with pancreatic cancer in Denmark at an institutional and national level.

Study population: Since May 1, 2011, all patients with microscopically verified ductal adenocarcinoma of the pancreas have been registered in the database. As of June 30, 2014, the total number of patients registered was 2,217. All data are cross-referenced with the Danish Pathology Registry and the Danish Patient Registry to ensure the completeness of registrations.

Main variables: The main registered variables are patient demographics, performance status, diagnostic workup, histological and/or cytological diagnosis, and clinical tumor stage. The following data on treatment are registered: type of operation, date of first adjuvant, neoadjuvant, and first palliative chemo- or chemoradiation therapy, and dates for milestones in referrals, diagnostic workup, treatment decisions, and treatment. For patients undergoing resection, data on operative evaluation of tumor stage, histological diagnosis, and duration of hospital stay are registered.

Descriptive data: Death is monitored using data from the Danish Civil Registry. This registry monitors the survival status of the Danish population, and the registration is virtually complete. All data in the database are audited by all participating institutions, with respect to baseline characteristics, key indicators, and survival. The results are published annually.

Conclusion: The Danish Pancreatic Cancer Database has registered data on 2,217 patients with microscopically verified ductal adenocarcinoma of the pancreas. The data have been obtained nationwide over a period of 4 years and 2 months. The completeness of registration was 82%. The observed overall 3-year survival after diagnosis was 6%.

Keywords: national database; pancreatic cancer; survival.

PubMed Disclaimer

Conflict of interest statement

The authors report no conflicts of interest in this work.

Figures

Figure 1
Figure 1
Overall survival of patients with a histological diagnosis of pancreatic cancer in Denmark during a 3-year period. Notes: Overall survival for 2,217 patients with pancreatic cancer diagnosed between May 1, 2011, and June 30, 2014. Median survival was 5.8 months (95% CI: 5.6–6.3). A total of 509 (23%) patients were still alive in September 2014, with a median observation time of 5 months. Abbreviation: CI, confidence interval.
See this image and copyright information in PMC

References

    1. Siegel R, Naishadham D, Jemal A. Cancer statistics, 2013. CA Cancer J Clin. 2013;63(1):11–30. - PubMed
    1. Ferlay J, Steliarova-Foucher E, Lortet-Tieulent J, et al. Cancer incidence and mortality patterns in Europe: estimates for 40 countries in 2012. Eur J Cancer. 2013;49(6):1374–1403. - PubMed
    1. Erichsen R, Lash TL, Hamilton-Dutoit SJ, Bjerregaard B, Vyberg M, Pedersen L. Existing data sources for clinical epidemiology: the Danish National Pathology Registry and Data Bank. Clin Epidemiol. 2010;2:51–56. - PMC - PubMed
    1. Pedersen CB. The Danish Civil Registration System. Scand J Public Health. 2011;39(7 suppl):22–25. - PubMed
    1. Schmidt M, Pedersen L, Sorensen HT. The Danish Civil Registration System as a tool in epidemiology. Eur J Epidemiol. 2014;29(8):541–549. - PubMed