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Case Reports
. 2016 Oct 4:18:29-31.
doi: 10.1016/j.gore.2016.10.001. eCollection 2016 Nov.

Primary gynecological non-Hodgkin's lymphoma: A differential diagnosis of a pelvic mass

Shilpa Vijayakumar  1 , Eli Serur  2 , Bahar Bybordi  3 , Nisha Lakhi  1
Affiliations
Case Reports

Primary gynecological non-Hodgkin's lymphoma: A differential diagnosis of a pelvic mass

Shilpa Vijayakumar et al. Gynecol Oncol Rep. .

Abstract

Primary Non-Hodgkin's lymphoma (NHL) can mimic gynecological malignancy, presenting as a pelvic mass in any organ of the female genital tract. Patients can present with elevated CA-125 and may lack the classical symptoms associated with lymphoma, such as fatigue, fever, night sweats and weight loss. We describe five patients that presented with primary NHL of the genital tract. Patients 1, 2, and 3 were not diagnosed pre-operatively, and underwent unnecessary cytoreductive surgery, while patients 4 and 5 were diagnosed by pre-operative biopsy. The diagnosis of primary pelvic lymphoma should be in the differential diagnosis of gynecological malignancies. Awareness of the disease and pre-operative diagnosis can be beneficial, as the patient may be able to avoid unnecessary staging operations and disease cytoreduction.

Keywords: CA-125; Non-Hodgkin's lymphoma; Pelvic mass, gynecological origin.

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References

    1. Ahmad A.K., Hui P., Litkouhi B., Azodi M., Rutherford T., McCarthy S., Xu M.L., Schwartz P.E., Ratner E. Institutional review of primary non-Hodgkin lymphoma of the female genital tract: a 33-year experience. Int. J. Gynecol. Cancer. 2014 Sep;24(7):1250–1255. - PMC - PubMed
    1. Allen G.W., Forouzannia A., Bailey H.H., Howard S.P. Non Hodgkin's lymphoma presenting as pelvic mass with elevated CA-125. Gynecol. Oncol. 2004 Sep;94(3):811–813. - PubMed
    1. Armitage J.O., Weisenburger D.D. New approach to classifying non-Hodgkin's lymphomas: clinical features of the major histologic subtypes. Non-Hodgkin's lymphoma classification project. J. Clin. Oncol. 1998 Aug;16(8):2780–2795. - PubMed
    1. Bairey O., Blickstein D., Stark P., Prokocimer M., Nativ H.M., Kirgner I., Shaklai M. Serum CA 125 as a prognostic factor in non-Hodgkin's lymphoma. Leuk. Lymphoma. 2003 Oct;44(10):1733–1738. - PubMed
    1. Chen R., Yu Z., Zhang H., Ding J., Chen B. Primary malignant lymphoma of the uterus and broad ligament: a case report and review of literature. Onco Targets Ther. 2015 Jan 29;8:265–268. - PMC - PubMed

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