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Editorial
. 2017 Feb;16(3):245-246.
doi: 10.1080/15384101.2016.1252584. Epub 2016 Nov 10.

Citron kinase in spindle orientation and primary microcephaly

Marta Gai  1 , Ferdinando Di Cunto  1
Affiliations
Editorial

Citron kinase in spindle orientation and primary microcephaly

Marta Gai et al. Cell Cycle. 2017 Feb.
No abstract available

Keywords: ASPM; astral microtubules; citron kinase; cytokinesis; primary microcephaly; spindle orientation.

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Figures

Figure 1.
Figure 1.
CITK regulates mitotic spindle orientation. The cytokinesis regulator CITK is recruited by the microcephaly gene ASPM to the mitotic spindle of neural progenitor cells, where it promotes the correct organization of astral MT, thus allowing the anchorage of the spindle to the cell cortex required for a proper orientation.
See this image and copyright information in PMC

References

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