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. 2016 Oct;10(4):522-531.

Clinical Utility of Esophageal manometry in the patients with dysphagia - Experience from Sudan

Amin M Abbas  1 , Sami Medani  1 , Tajeldin M Abdallah  2 , Gasim I Gasim  3
Affiliations

Clinical Utility of Esophageal manometry in the patients with dysphagia - Experience from Sudan

Amin M Abbas et al. Int J Health Sci (Qassim). 2016 Oct.

Abstract

Objectives: The aim of this study was to assess the clinical utility of esophageal manometry among Sudanese patients presenting to the National Centre for Gastrointestinal and Liver Diseases, Ibn Sina Hospital, Khartoum, Sudan.

Methodology: Consecutive patients referred for esophageal manometry at the aforementioned center from July 2008 through January 2011 were included in the study. Manometric studies were done after stopping medicines with a known effect on esophageal motility and an overnight fast. Immediately before the manometric study, the patients' history and clinical examination were recorded using a structured questionnaire.

Results: The major referral reason was the investigation of dysphagia in 78 patients (60.5%), followed by the evaluation of Gastroesophageal reflux disease (GERD) in 39 patients (30%), while 11 patients (9%) were referred because of non-cardiac chest pain. The manometric diagnosis in the 78 patients with dysphagia, where 51(65.4%) had achalasia, 13(16.7%) had nonspecific motility disorder, the remaining percentage was formed by GERD diffuse esophageal spasm, connective tissue disease, Nutcracker esophagus, hypertensive lower esophageal sphincter, patient manometry suggestive of myasthenia gravis, and normal manometry.

Conclusion: GERD and Achalasia were the commonest conditions among the study group. Patients presenting with achalasia manifest the same clinical symptoms as published in the literature. The leading abnormality predisposing to GERD was hypotensive lower esophageal sphincter and weak esophageal clearance function. GERD was main cause of non-cardiac chest pain in the study population. However, it is difficult to generalize the findings of this study for the whole country since it was a single center study.

Keywords: GERD; Sudan; achalasia; esophageal manometry; non-cardiac chest pain.

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Figures

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Fig. 1
Distribution of The Study Population by Age
Fig. 2
Fig. 2
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Fig. 3
Age Groups for Patients with Achalasia
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Fig. 4
Clinical profile of 51 patients with Achalasia
Fig. 5
Fig. 5
Therapy for Achalasia Patients
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References

    1. Kronecker H, Meltzer SJ. Der schluckmechanismus, seineerregung und seine hemmung. Arch GesAnatPhysiol (suppl) 1983;7:328–332.
    1. Code CF, Creamer B, Schegel JF. An Atlas of Esophageal Motility in Health and Disease. Proc R Soc Med. 1959;52:221.
    1. Bredenoord AJ, Smout AJ. High-resolution manometry of the esophagus: more than a colorful view on esophageal motility? Expert Rev Gastroenterol Hepatol. 2007;1:61–9. - PubMed
    1. Ergun GA, Kahrilas PJ. Clinical applications of esophageal manometry and pH monitoring. Am J Gastroenterol. 1996;91:1077–1089. - PubMed
    1. Pandolfino JE, Kahrilas PJ. AGA technical review: clinical use of esophageal manometry. Gastroenterology. 2005;128:209–224. - PubMed

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