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Review
. 2016 Nov 8:3:33.
doi: 10.1186/s40779-016-0104-3. eCollection 2016.

Early prevention of trauma-related infection/sepsis

Xiao-Yuan Ma #  1 , Li-Xing Tian #  1 , Hua-Ping Liang  1
Affiliations
Review

Early prevention of trauma-related infection/sepsis

Xiao-Yuan Ma et al. Mil Med Res. .

Abstract

Trauma still represents one of the major causes of death worldwide. Despite the reduction of post-traumatic sepsis over the past two decades, the mortality of septic trauma inpatients is still high (19.5-23 %). Early prevention of sepsis development can aid in the subsequent treatment of patients and help improve their outcomes. To date, the prevention of trauma-related infection/sepsis has mainly included infection prevention (e.g., surgical management, prophylactic antibiotics, tetanus vaccination, immunomodulatory interventions) and organ dysfunction prevention (e.g., pharmaceuticals, temporary intravascular shunts, lung-protective strategies, enteral immunonutrition, acupuncture). Overall, more efficient ways should be developed to prevent trauma-related infection/sepsis.

Keywords: Infection; Prevention; Sepsis; Trauma.

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References

    1. Morrison JJ, Yapp LZ, Beattie A, Devlin E, Samarage M, McCaffer C, et al. The epidemiology of Scottish trauma: A comparison of pre-hospital and in-hospital deaths, 2000 to 2011. Surgeon. 2016;14(1):1–6. doi: 10.1016/j.surge.2015.02.001. - DOI - PubMed
    1. Binkowska AM, Michalak G, Slotwinski R. Current views on the mechanisms of immune responses to trauma and infection. Cent Eur J Immunol. 2015;40(2):206–16. doi: 10.5114/ceji.2015.52835. - DOI - PMC - PubMed
    1. Giannou C, Baldan M. War Surgery: Working with limited resources in armed conflict and other situations of violence, vol. 1. Geneva: ICRC; 2010;1:253–266.
    1. Edlich RF, Rodeheaver GT, Thacker JG, Lin KY, Drake DB, Mason SS, et al. Revolutionary advances in the management of traumatic wounds in the emergency department during the last 40 years: part II. J Emerg Med. 2010;38(2):201–7. doi: 10.1016/j.jemermed.2008.11.016. - DOI - PubMed
    1. Masterson TM, Rodeheaver GT, Morgan RF, Edlich RF. Bacteriologic evaluation of electric clippers for surgical hair removal. Am J Surg. 1984;148(3):301–2. doi: 10.1016/0002-9610(84)90458-6. - DOI - PubMed

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