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Review
. 2016 Nov 10;17(11):1877.
doi: 10.3390/ijms17111877.

Dietary Strategies Implicated in the Prevention and Treatment of Metabolic Syndrome

Rocio de la Iglesia  1 , Viviana Loria-Kohen  2 , Maria Angeles Zulet  3   4 , Jose Alfredo Martinez  5   6 , Guillermo Reglero  7 , Ana Ramirez de Molina  8
Affiliations
Review

Dietary Strategies Implicated in the Prevention and Treatment of Metabolic Syndrome

Rocio de la Iglesia et al. Int J Mol Sci. .

Abstract

Metabolic syndrome (MetS) is established as the combination of central obesity and different metabolic disturbances, such as insulin resistance, hypertension and dyslipidemia. This cluster of factors affects approximately 10%-50% of adults worldwide and the prevalence has been increasing in epidemic proportions over the last years. Thus, dietary strategies to treat this heterogenic disease are under continuous study. In this sense, diets based on negative-energy-balance, the Mediterranean dietary pattern, n-3 fatty acids, total antioxidant capacity and meal frequency have been suggested as effective approaches to treat MetS. Furthermore, the type and percentage of carbohydrates, the glycemic index or glycemic load, and dietary fiber content are some of the most relevant aspects related to insulin resistance and impaired glucose tolerance, which are important co-morbidities of MetS. Finally, new studies focused on the molecular action of specific nutritional bioactive compounds with positive effects on the MetS are currently an objective of scientific research worldwide. The present review summarizes some of the most relevant dietary approaches and bioactive compounds employed in the treatment of the MetS to date.

Keywords: bioactive compounds; dietary strategies; metabolic syndrome.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Diagram of Metabolic syndrome comorbidities and dietary strategies and bioactive compounds described.
See this image and copyright information in PMC

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