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Review
. 2016 Dec;43(4):773-782.
doi: 10.1016/j.clp.2016.07.011. Epub 2016 Sep 28.

The Role of Caffeine in Noninvasive Respiratory Support

Nicole R Dobson  1 , Ravi Mangal Patel  2
Affiliations
Review

The Role of Caffeine in Noninvasive Respiratory Support

Nicole R Dobson et al. Clin Perinatol. 2016 Dec.

Abstract

Caffeine is one of the most commonly prescribed medications in preterm neonates and is widely used to treat or prevent apnea of prematurity. Caffeine therapy is safe, effectively decreases apnea, and improves short- and long-term outcomes in preterm infants. In this review, the authors summarize the role of caffeine therapy for preterm infants receiving noninvasive respiratory support. As caffeine is already widely used, recent data are summarized that may guide clinicians in optimizing the use of caffeine therapy, with a review of the timing of initiation, dose, and duration of therapy.

Keywords: Apnea; Bronchopulmonary dysplasia; Caffeine; Noninvasive ventilation; Premature infant.

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Conflict of interest statement

The authors have no relevant conflicts of interest.

Figures

Figure 1
Figure 1. Effects of Caffeine on Neonatal Respiratory Health: Potential Mechanisms
Study references are noted in the bottom right of each box.
See this image and copyright information in PMC

References

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