Pulmonary and pleural pathology: Contributions of Dr. Louis "Pepper" Dehner

Abstract

Dr. Louis Dehner is an internationally renowned surgical pathologist who has published multiple textbooks and has authored or co-authored nearly 400 original articles in the medical literature. While many think of him as a pediatric pathologist, he has contributed to the literature across virtually the entire breadth of surgical pathology, and the lung and pleura is no exception. This review will highlight Dr. Dehner׳s contributions to the pulmonary and pleural pathology literature in the areas of infectious disease, medical lung disease and transplant pathology, and a number of neoplasms of the lung and pleura, with the remainder of this manuscript dedicated to the still evolving story of the pleuropulmonary blastoma as the signature contribution of his long and distinguished career.

Keywords: DICER1; Fetal lung interstitial tumor; Inflammatory myofibroblastic tumor; Pleuropulmonary blastoma; Pneumocystis; Surfactant deficiency.