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Randomized Controlled Trial
. 2017 Mar 1;45(3):298-300.
doi: 10.1016/j.ajic.2016.10.007. Epub 2016 Nov 11.

Impact of chlorhexidine bathing on methicillin-resistant Staphylococcus aureus incidence in an endemic chronic care setting: A randomized controlled trial

Chingiz M Amirov  1 , Malcolm A Binns  2 , Latha E Jacob  3 , Heather L Candon  3
Affiliations
Randomized Controlled Trial

Impact of chlorhexidine bathing on methicillin-resistant Staphylococcus aureus incidence in an endemic chronic care setting: A randomized controlled trial

Chingiz M Amirov et al. Am J Infect Control. .

Abstract

We postulated that bathing with 2% chlorhexidine-impregnated antiseptic washcloths could reduce methicillin-resistant Staphylococcus aureus (MRSA) incidence among chronic care patients compared with nonantiseptic bathing. A total of 122 patients on 3 hospital units were enrolled in a 12-month, cluster-randomized, open-label, controlled trial, with 8 patients becoming MRSA positive. The 2% chlorhexidine-impregnated antiseptic washcloths reduced incidence by 71% (0.1 vs 0.44 cases per 1,000 patient days) (P = .14; Fisher exact). The detected difference was not statistically significant because of a low number of observed events.

Keywords: Chlorhexidine bathing; Chronic care; MRSA.

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