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Editorial
. 2016 Sep 20;3(2):e000385.
doi: 10.1136/openhrt-2015-000385. eCollection 2016.

The importance of a balanced ω-6 to ω-3 ratio in the prevention and management of obesity

Artemis P Simopoulos  1 , James J DiNicolantonio  2
Affiliations
Editorial

The importance of a balanced ω-6 to ω-3 ratio in the prevention and management of obesity

Artemis P Simopoulos et al. Open Heart. .
No abstract available

Keywords: GENETICS; LIPIDS; METABOLIC MEDICINE.

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Figures

Figure 1
Figure 1
Hypothetical scheme of fat, fatty acid (ω6, ω3, trans and total) intake (as per cent of calories from fat) and intake of vitamins E and C (mg/day). Data were extrapolated from cross-sectional analyses of contemporary hunter-gatherer populations and from longitudinal observations and their putative changes during the preceding 100 years.
Figure 2
Figure 2
Desaturation and elongation of ω-3 and ω-6 fatty acids. The enzymes Δ6 desaturase and Δ5 desaturase are encoded by FADS2 and FADS1, respectively. AA, arachidonic acid; DHA, docosahexaenoic acid; EPA, eicosapentaenoic acid; FAD, fatty acid desaturase; GLA, γ-linoleic acid.
Figure 3
Figure 3
The fatty acid content of common fats and oils. The chart shows the percentage of saturated fatty acids, monounsaturated fatty acids, linoleic acid and α-linolenic acid in 13 commonly used fats and oils.
See this image and copyright information in PMC

References

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    1. Simopoulos AP. Dietary omega-3 fatty acid deficiency and high fructose intake in the development of metabolic syndrome, brain metabolic abnormalities, and non-alcoholic fatty liver disease. Nutrients 2013;5:2901–23. 10.3390/nu5082901 - DOI - PMC - PubMed
    1. Simopoulos AP. The impact of the Bellagio report on healthy agriculture, healthy nutrition, healthy people: scientific and policy aspects and the international network of centers for genetics, nutrition and fitness for health. J Nutrigenet Nutrigenomics 2015;7:191–211. 10.1159/000375495 - DOI - PubMed

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