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. 2016 Nov 14;30(5):665-667.
doi: 10.1016/j.ccell.2016.10.013.

Unraveling the DNA Methylome in Mantle Cell Lymphoma: New Insights into the Cellular Origin

Larry Mansouri  1 , Richard Rosenquist  2
Affiliations
Free article

Unraveling the DNA Methylome in Mantle Cell Lymphoma: New Insights into the Cellular Origin

Larry Mansouri et al. Cancer Cell. .
Free article

Abstract

Our understanding of the DNA methylome and its impact on cancer evolution and disease progression is rapidly evolving. In this issue of Cancer Cell, Queirós et al. provide a detailed characterization of the DNA methylome in mantle cell lymphoma and reveal novel molecular subtypes, potentially with different cellular origins.

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  • Decoding the DNA Methylome of Mantle Cell Lymphoma in the Light of the Entire B Cell Lineage.
    Queirós AC, Beekman R, Vilarrasa-Blasi R, Duran-Ferrer M, Clot G, Merkel A, Raineri E, Russiñol N, Castellano G, Beà S, Navarro A, Kulis M, Verdaguer-Dot N, Jares P, Enjuanes A, Calasanz MJ, Bergmann A, Vater I, Salaverría I, van de Werken HJG, Wilson WH, Datta A, Flicek P, Royo R, Martens J, Giné E, Lopez-Guillermo A, Stunnenberg HG, Klapper W, Pott C, Heath S, Gut IG, Siebert R, Campo E, Martín-Subero JI. Queirós AC, et al. Cancer Cell. 2016 Nov 14;30(5):806-821. doi: 10.1016/j.ccell.2016.09.014. Cancer Cell. 2016. PMID: 27846393 Free PMC article.

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