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Editorial
. 2017 Jan;14(1):1-5.
doi: 10.1080/17425247.2017.1262346. Epub 2016 Nov 28.

Cancer nanomedicines: oversold or underappreciated?

Roy van der Meel  1   2 , Twan Lammers  3   4   5 , Wim E Hennink  5
Affiliations
Editorial

Cancer nanomedicines: oversold or underappreciated?

Roy van der Meel et al. Expert Opin Drug Deliv. 2017 Jan.
No abstract available

Keywords: Cancer nanomedicines; Clinical translation; Clinical trials; Combination treatment; Drug delivery; Drug targeting; EPR effect; Triggered release.

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Conflict of interest statement

Declaration of interest

TL is a member of the scientific advisory board of Cristal Therapeutics. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.

References

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    1. Thomas A, Teicher BA, Hassan R. Antibody-drug conjugates for cancer therapy. Lancet Oncol. 2016;17:e254–62. - PMC - PubMed
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    1. Matsumura Y, Maeda H. A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. Cancer Res. 1986;46:6387–92. [Fundamental study which demonstrated the accumulation of macromolecules in solid tumors.] - PubMed
    1. Wilhelm S, Tavares AJ, Dai Q, et al. Analysis of nanoparticle delivery to tumours. Nature Reviews Materials. 2016 doi: 10.1038/natrevmats.2016.14. [Recent meta-analysis of pre-clinical studies comparing tumor accumulation of cancer nanomedicines.] - DOI

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