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Case Reports
. 2016;55(22):3337-3340.
doi: 10.2169/internalmedicine.55.6852. Epub 2016 Nov 15.

Development of Pulmonary Artery Aneurysms Due to Behçet's Disease and Resolution after Treatment

Hidenori Kage  1 , Yasushi Goto, Yosuke Amano, Kosuke Makita, Hideaki Isago, Kouichi Kobayashi, Osamu Narumoto, Reiko Okudaira, Goh Tanaka, Kazutaka Takami, Nobuya Ohishi, Takahide Nagase
Affiliations
Case Reports

Development of Pulmonary Artery Aneurysms Due to Behçet's Disease and Resolution after Treatment

Hidenori Kage et al. Intern Med. 2016.

Abstract

We herein describe a patient with Behçet's disease in whom we followed the development and resolution of pulmonary artery aneurysms. He presented with intermittent hemoptysis, pulmonary thromboembolism was initially diagnosed, and anticoagulant therapy was started. Over the next several months, the expansion of pulmonary arteries was noted. Five months after his initial admission, he was readmitted for massive hemoptysis, and further examinations revealed that he had Behçet's disease. Corticosteroids and intravenous cyclophosphamide were started. Over the next five months, the pulmonary artery aneurysms and thrombosis resolved. The development of pulmonary artery aneurysms led to the diagnosis of Behçet's disease, and they resolved after immunosuppressive therapy.

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Figures

Figure 1.
Figure 1.
Chest CT at first admission (a), second admission (b), three months after the second admission (c), and five months after the second admission (d). The arrows indicate the left pulmonary artery.
Figure 2.
Figure 2.
Expansion of the pulmonary arteries. The right and left pulmonary arteries (arrows) had slightly expanded two months after first admission and clearly expanded five months after first admission (one week before second admission).
Figure 3.
Figure 3.
Resolution of the pulmonary artery aneurysms. At second admission, chest X-ray showed consolidation in the right lower lung field (left). The left pulmonary artery aneurysm (arrows) had shrunk in size at 3 months after beginning therapy with corticosteroids and cyclophosphamide. The aneurysm appeared to be resolved at the end of the cyclophosphamide pulse therapy regimen, which was five months after starting treatment.
See this image and copyright information in PMC

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