Active control of intracellular pH
- PMID: 27855
- DOI: 10.1016/0034-5687(78)90084-1
Active control of intracellular pH
Abstract
When the interior of a squid giant axon is loaded with acid, the cell responds by extruding that acid in an energy-requiring process. Our results indicate that this acid extrusion is accomplished by exchanging external HCO3- for internal Cl- at the expense of ATP.