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. 2017 Apr;65(4):754-762.
doi: 10.1111/jgs.14671. Epub 2016 Nov 15.

Beta-Blocker Use in U.S. Nursing Home Residents After Myocardial Infarction: A National Study

Andrew R Zullo  1 , Yoojin Lee  1 , Lori A Daiello  1 , Vincent Mor  1   2 , W John Boscardin  3   4   5 , David D Dore  1   6 , Yinghui Miao  3   4 , Kathy Z Fung  3   4 , Kiya D R Komaiko  3   4 , Michael A Steinman  3   4
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Beta-Blocker Use in U.S. Nursing Home Residents After Myocardial Infarction: A National Study

Andrew R Zullo et al. J Am Geriatr Soc. 2017 Apr.

Abstract

Objectives: To evaluate how often beta-blockers were started after acute myocardial infarction (AMI) in nursing home (NH) residents who previously did not use these drugs and to evaluate which factors were associated with post-AMI use of beta-blockers.

Design: Retrospective cohort using linked national Minimum Data Set assessments; Online Survey, Certification and Reporting records; and Medicare claims.

Setting: U.S. NHs.

Participants: National cohort of 15,720 residents aged 65 and older who were hospitalized for AMI between May 2007 and March 2010, had not taken beta-blockers for at least 4 months before their AMI, and survived 14 days or longer after NH readmission.

Measurements: The outcome was beta-blocker initiation within 30 days of NH readmission.

Results: Fifty-seven percent (n = 8,953) of residents initiated a beta-blocker after AMI. After covariate adjustment, use of beta-blockers was less in older residents (ranging from odds ratio (OR) = 0.89, 95% confidence interval (CI) = 0.79-1.00 for aged 75-84 to OR = 0.65, 95% CI = 0.54-0.79 for ≥95 vs 65-74) and less in residents with higher levels of functional impairment (dependent or totally dependent vs independent to limited assistance: OR = 0.84, 95% CI = 0.75-0.94) and medication use (≥15 vs ≤10 medications: OR = 0.89, 95% CI = 0.80-0.99). A wide variety of resident and NH characteristics were not associated with beta-blocker use, including sex, cognitive function, comorbidity burden, and NH ownership.

Conclusion: Almost half of older NH residents in the United States do not initiate a beta-blocker after AMI. The absence of observed factors that strongly predict beta-blocker use may indicate a lack of consensus on how to manage older NH residents, suggesting the need to develop and disseminate thoughtful practice standards.

Keywords: beta-blockers; drug utilization; elderly; myocardial infarction; nursing homes.

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Figures

Figure 1
Figure 1
Flow diagram of resident inclusion and exclusion in study cohort.
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