Polymorphonuclear leukocyte chemiluminescence response in HLA-B27 positive and negative arthritic patients
- PMID: 2786236
- DOI: 10.1007/BF00270985
Polymorphonuclear leukocyte chemiluminescence response in HLA-B27 positive and negative arthritic patients
Abstract
The polymorphonuclear leukocyte (PMN) chemiluminescence (CL) response to opsonized zymosan reflecting the C3b/C3bi-receptor-mediated PMN respiratory burst activation was studied in 99 arthritic patients typed for the HLA-B27 antigen. The results indicate that the B27 antigen per se is not associated with disturbances in PMN CL response. However, the erythrocyte sedimentation rate showed a correlation with CL, suggesting that the activity of arthritic disease may affect the PMN CL response.
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