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. 2017 Jun;39(6):1234-1238.
doi: 10.1002/hed.24590. Epub 2016 Nov 15.

Free thyroid transfer: Short-term results of a novel procedure to prevent post-radiation hypothyroidism

Jeffrey Harris  1 , Brittany Barber  1 , Hani Almarzouki  1   2 , Rufus Scrimger  3 , Jacques Romney  4 , Daniel O'Connell  1 , Mark Urken  5 , Hadi Seikaly  1
Affiliations

Free thyroid transfer: Short-term results of a novel procedure to prevent post-radiation hypothyroidism

Jeffrey Harris et al. Head Neck. 2017 Jun.

Abstract

Background: The incidence of radiation-induced hypothyroidism (RIH) in patients with head and neck cancer is >50%. The purpose of this study was to assess the long-term efficacy of free thyroid transfer (FTT) for prevention of RIH in patients with head and neck cancer.

Methods: Hemithyroid dissection was completed in 10 patients with advanced head and neck cancer undergoing ablation, radial forearm free flap (RFFF) reconstruction, and postoperative radiotherapy (RT). The hemithyroid was anastomosed to the donor site vessels in the forearm. Thyroid laboratory testing and technetium (Tc) scans were performed 6 weeks and 12 months postoperatively to establish functional integrity.

Results: FTT was successfully performed in 9 of 10 recruited patients. Postoperative Tc scans demonstrated strong Tc uptake in the forearm donor site at 6 weeks and 12 months in all patients who underwent transplantations.

Conclusion: FTT is feasible with maintenance of function, and may represent a novel strategy for prevention of RIH. © 2016 Elsevier Head & Neck Published by Wiley Periodicals, Inc. Head Neck 39: 1234-1238, 2017.

Keywords: head neck cancer; radiation-induced hypothyroidism; thyroid.

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Figures

Figure 1
Figure 1
Hemithyroid dissection with preservation of arterial and venous anastomotic vessels.
Figure 2
Figure 2
Transferred hemithyroid anastomosed to forearm donor site vessels with implantable Cook‐Schwartz Doppler probes.
Figure 3
Figure 3
Tc uptake at the transplanted forearm site.
See this image and copyright information in PMC

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