Discovery of Ibomycin, a Potent Antifungal Weapon
- PMID: 27863218
- DOI: 10.1016/j.chembiol.2016.11.001
Discovery of Ibomycin, a Potent Antifungal Weapon
Abstract
In this issue of Cell Chemical Biology, Robbins et al. (2016) identify ibomycin, a unique compound with antifungal activity. Microbial physiological and genetic studies suggest that endocytic trafficking might be the site of action for this lead antifungal compound.
Copyright © 2016 Elsevier Ltd. All rights reserved.
Comment on
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Discovery of Ibomycin, a Complex Macrolactone that Exerts Antifungal Activity by Impeding Endocytic Trafficking and Membrane Function.Cell Chem Biol. 2016 Nov 17;23(11):1383-1394. doi: 10.1016/j.chembiol.2016.08.015. Epub 2016 Oct 13. Cell Chem Biol. 2016. PMID: 27746129