The Good and Bad of RNA:DNA Hybrids in Double-Strand Break Repair
- PMID: 27863224
- DOI: 10.1016/j.molcel.2016.11.010
The Good and Bad of RNA:DNA Hybrids in Double-Strand Break Repair
Abstract
Transcription and genome stability have somewhat of a love-hate relationship. In a recent issue of Cell, Ohle et al. (2016) demonstrate a previously unappreciated mechanism by which transcription and RNA contribute to genome stability.
Copyright © 2016 Elsevier Inc. All rights reserved.
Comment on
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Transient RNA-DNA Hybrids Are Required for Efficient Double-Strand Break Repair.Cell. 2016 Nov 3;167(4):1001-1013.e7. doi: 10.1016/j.cell.2016.10.001. Epub 2016 Oct 27. Cell. 2016. PMID: 27881299
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